BDBM26028 4-({2-[(3-tert-butylphenyl)(methyl)amino]-1H-1,3-benzodiazol-5-yl}oxy)-N-methylpyridine-2-carboxamide::arylaminobenzimidazole, 23

SMILES CNC(=O)c1cc(Oc2ccc3n(C)c(Nc4cccc(c4)C(C)(C)C)nc3c2)ccn1

InChI Key InChIKey=SILANKVZJSUJHJ-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 26028   

TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Novartis

LigandPNGBDBM26028(4-({2-[(3-tert-butylphenyl)(methyl)amino]-1H-1,3-b...)
Affinity DataIC50:  4nMpH: 7.8 T: 2°CAssay Description:To measure compound inhibitor effects on the ability of Raf enzymes to phosphorylate the Mek substrate, a capture ELISA utilizing streptavidin-coated...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed